The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus

The antituberculosis drug telacebec is ineffective against Mycobacterium abscessus. A recent study suggested that TB47, a telacebec analogue, potentiated the efficacy of clofazimine against M. abscessus. Here, we report that TB47 not only is ineffective against M. abscessus in vitro but also does no...

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Bibliographic Details
Main Authors: Sorayah, Ria, Moraski, Garret C., Barkan, Daniel, Pethe, Kevin
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/153678