High-payload buccal delivery system of amorphous curcumin-chitosan nanoparticle complex in hydroxypropyl methylcellulose and starch films
Oral delivery of curcumin (CUR) has limited effectiveness due to CUR's poor systemic bioavailability caused by its first-pass metabolism and low solubility. Buccal delivery of CUR nanoparticles can address the poor bioavailability issue by virtue of avoidance of first-pass metabolism and solubi...
Main Authors: | , |
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Format: | Journal Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/154017 |