High-payload buccal delivery system of amorphous curcumin-chitosan nanoparticle complex in hydroxypropyl methylcellulose and starch films

Oral delivery of curcumin (CUR) has limited effectiveness due to CUR's poor systemic bioavailability caused by its first-pass metabolism and low solubility. Buccal delivery of CUR nanoparticles can address the poor bioavailability issue by virtue of avoidance of first-pass metabolism and solubi...

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Bibliographic Details
Main Authors: Lim, Li Ming, Hadinoto, Kunn
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/154017

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