Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

Cell state transitions control the functional behavior of cancer cells. Epithelial-to-mesenchymal transition (EMT) confers cancer stem cell-like properties, enhanced tumorigenicity and drug resistance to tumor cells, while mesenchymal-epithelial transition (MET) reverses these phenotypes. Using high...

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Bibliographic Details
Main Authors: Loo, Ser Yue, Toh, Li Ping, Xie, William Haowei, Pathak, Elina, Tan, Wilson, Ma, Siming, Lee, May Yin, Shatishwaran, S., Yeo, Joanna Zhen Zhen, Yuan, Ju, Ho, Yin Ying, Peh, Esther Kai Lay, Muniandy, Magendran, Torta, Federico, Chan, Jack, Tan, Tira J., Sim, Yirong, Tan, Veronique, Tan, Benita, Madhukumar, Preetha, Yong, Wei Sean, Ong, Kong Wee, Wong, Chow Yin, Tan, Puay Hoon, Yap, Yoon Sim, Deng, Lih-Wen, Dent, Rebecca, Foo, Roger, Wenk, Markus R., Lee, Soo Chin, Ho, Ying Swan, Lim, Elaine Hsuen, Tam, Wai Leong
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Biological sciences
Epithelial-Mesenchymal Transition
Retinoic Acid
Online Access:https://hdl.handle.net/10356/154360

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https://hdl.handle.net/10356/154360

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