Paracrine effect of TAK1 in fibroblasts on the oncogenic potential of adjacent epithelia.
Among the different cell types of the stroma, fibroblasts are the key contributors of paracrine signals which govern epithelial homeostasis. Transforming growth factor-beta (TGFβ) is one such signal which exhibits autocrine and paracrine effects. Recent findings have shown that TGFβ signaling in fib...
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Format: | Final Year Project (FYP) |
Language: | English |
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2009
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Online Access: | http://hdl.handle.net/10356/15455 |