Towards understanding the mode of action of the cytotoxic triosmium carbonyl cluster Os₃(CO)₁₀(NCCH₃)₂ : Its reactivity with amino acids and oligopeptides

The reactions of the triosmium carbonyl cluster Os₃(CO)₁₀(NCCH₃)₂ (1) with a number of protected amino acids, tri- and pentapeptides were examined. The results show that reaction with the side chains follow the order: -SH > -COOH > -CONH₂, and there is a slight preference for the longer side c...

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Bibliographic Details
Main Authors: Lee J.J.Y., Leong W.K.
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/154584