Amide-directed C-H sodiation by a sodium hydride/iodide composite

Amide-directed C-H sodiation by a sodium hydride/iodide composite

A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.

Bibliographic Details
Main Authors: Huang, Yinhua, Chan, Guo Hao, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Amides
Arenes
Online Access:https://hdl.handle.net/10356/154856

Internet

https://hdl.handle.net/10356/154856

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