Hydrodehalogenation of haloarenes by a sodium hydride-iodide composite

A simple protocol for hydrodebromination and -deiodination of halo(hetero)arenes was enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process.

Bibliographic Details
Main Authors: Ong, Derek Yiren, Tejo, Ciputra, Xu, Kai, Hirao, Hajime, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/154861