Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3

Flavivirus is a genus of the Flaviviridae family which includes significant emerging and re-emerging human disease-causing arboviruses such as dengue and Zika viruses. Flaviviral non-structural protein 3 (NS3) protease-helicase plays essential roles in viral replication and is an attractive antivira...

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Bibliographic Details
Main Authors: Phoo, Wint Wint, El Sahili, Abbas, Zhang, ZhenZhen, Chen, Ming Wei, Liew, Chong Wai, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Flavivirus NS3
Anti Viral Drug Discovery
Online Access:https://hdl.handle.net/10356/154890

Internet

https://hdl.handle.net/10356/154890

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