Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes
Aging is associated with declining body function and heightened risks of various diseases. The liver is the largest solid internal organ responsible for functions ranging from metabolism to detoxification. Hepatocytes perform most liver functions and hepatocyte polyploidization is a characteristic f...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2022
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Online Access: | https://hdl.handle.net/10356/155390 |