Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data
Modeling of signaling pathways is crucial for understanding and predicting cellular responses to drug treatments. However, canonical signaling pathways curated from literature are seldom context-specific and thus can hardly predict cell type-specific response to external perturbations; purely data-d...
Main Authors: | , , , , |
---|---|
Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2022
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/155401 |