Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data

Modeling of signaling pathways is crucial for understanding and predicting cellular responses to drug treatments. However, canonical signaling pathways curated from literature are seldom context-specific and thus can hardly predict cell type-specific response to external perturbations; purely data-d...

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Bibliographic Details
Main Authors: Liu, Hui, Zhang, Fan, Mishra, Shital Kumar, Zhou, Shuigeng, Zheng, Jie
Other Authors: School of Computer Science and Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155401