Structural and functional studies of peptide asparaginyl ligases

Asparaginyl endopeptidases are cysteine peptidases. Most AEPs are proteases, but some special AEPs known as peptide asparaginyl ligases (PALs), such as butelase 1, mediate peptide cyclization or ligation reactions. PALs and AEPs exhibit a high degree of amino acid sequence identity and structural si...

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Bibliographic Details
Main Author: Hu, Side
Other Authors: Julien Lescar
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155677