Structural and functional studies of peptide asparaginyl ligases
Asparaginyl endopeptidases are cysteine peptidases. Most AEPs are proteases, but some special AEPs known as peptide asparaginyl ligases (PALs), such as butelase 1, mediate peptide cyclization or ligation reactions. PALs and AEPs exhibit a high degree of amino acid sequence identity and structural si...
Main Author: | Hu, Side |
---|---|
Other Authors: | Julien Lescar |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2022
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/155677 |
Similar Items
Similar Items
-
Expanding the substrate specificity of peptide asparaginyl ligase
by: Chua, Niying
Published: (2023) -
Protein engineering using asparaginyl peptide ligases
by: Wang, Zhen
Published: (2023) -
Structural determinants for peptide-bond formation by asparaginyl ligases
by: Hemu, Xinya, et al.
Published: (2021) -
Engineering protein theranostics using bio-orthogonal asparaginyl peptide ligases
by: Wang, Zhen, et al.
Published: (2021) -
Expanding the scope of substrate specificity for peptide asparaginyl ligases
by: Lim, Ching Koon
Published: (2023)