Use of the Z-DNA binding domain of ADAR1 as a probe for nucleic acids in left-handed conformation
Both DNA and RNA can be in Z-conformation. Compared to classical B-DNA conformation, Z-DNA is in a higher energy state and studied extensively, so far mainly in vitro. It has been recognized that Z-DNA plays roles in many biological activities, including regulation of transcription, chromatin remode...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2009
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/15657 |