Characterization of binary and ternary complexes of filamin A domain FLNa-Ig21 with cytosolic tails of αMβ2 integrin

Integrins are a/B heterodimeric transmembrane receptors important for cell adhesion and migration. The cytosolic tails of integrin are essential for signalling and maintenance of its resting state. Integrin binding partners interact with the tails to control integrin activation, particularly the B t...

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Bibliographic Details
Main Author: Woo, Jia Hern
Other Authors: Surajit Bhattacharyya
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/156793