Chaperone-mediated formation of shell-like TDP-43 condensates

Transactivation response element DNA binding protein 43 (TDP-43), an RNA-binding protein is the major component of inclusion bodies in patients afflicted with Amyotrophic Lateral Sclerosis (ALS). A recent study established that a compromise in RNA-binding capacity of TDP-43, resulting from post-tra...

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Bibliographic Details
Main Author: Kong, Jian Hua
Other Authors: Choe Young Jun
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/156869