Hyaluronidase-1-mediated glycocalyx impairment underlies endothelial abnormalities in polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV), a subtype of age-related macular degeneration (AMD), is a global leading cause of vision loss in older populations. Distinct from typical AMD, PCV is characterized by polyp-like dilatation of blood vessels and turbulent blood flow in the choroid of the eye. G...

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Bibliographic Details
Main Authors: Wu, Kan Xing, Yeo, Natalie Jia Ying, Ng, Chun Yi, Chioh, Florence Wen Jing, Fan, Qiao, Tian, Xianfeng, Yang, Binxia, Narayanan, Gunaseelan, Tay, Hui Min, Hou, Han Wei, Dunn, Norris Ray, Su, Xinyi, Cheung, Gemmy Chui Ming, Cheung, Christine
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/160330