N-WASP attenuates cell proliferation and migration through ERK2-dependent enhanced expression of TXNIP

Neural Wiskott-Aldrich Syndrome Protein (N-WASP) regulates actin cytoskeleton remodeling. It has been known that reduced N-WASP expression in breast and colorectal cancers is associated with poor prognosis. Here, we found reduced N-WASP expression in squamous cell carcinoma (SCC) patient samples. Th...

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Bibliographic Details
Main Authors: Chung, Yat Joong, Salvi, Amrita, Kalailingam, Pazhanichamy, Alnawaz, Myra, Tan, Suat Hoon, Pan, Jiun Yit, Tan, Nguan Soon, Thanabalu, Thirumaran
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/160717