APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups

Background: Hypertriglyceridemia has emerged as a critical coronary artery disease (CAD) risk factor. Rare loss-of function (LoF) variants in apolipoprotein C-III have been reported to reduce triglycerides (TG) and are cardioprotective in American Indians and Europeans. However, there is a lack of d...

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Bibliographic Details
Main Authors: Goyal, Shiwali, Tanigawa, Yosuke, Zhang, Weihua, Chai, Jin-Fang, Almeida, Marcio, Sim, Xueling, Lerner, Megan, Chainakul, Juliane, Ramiu, Jonathan Garcia, Seraphin, Chanel, Apple, Blair, Vaughan, April, Muniu, James, Peralta, Juan, Lehman, Donna M., Ralhan, Sarju, Wander, Gurpreet S., Singh, Jai Rup, Mehra, Narinder K., Sidorov, Evgeny, Peyton, Marvin D., Blackett, Piers R., Curran, Joanne E., Tai, E Shyong, van Dam, Rob, Cheng, Ching-Yu, Duggirala, Ravindranath, Blangero, John, Chambers, John Campbell, Sabanayagam, Charumathi, Kooner, Jaspal S., Rivas, Manuel A., Aston, Christopher E., Sanghera, Dharambir K.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Mendelian Randomization
Asian Indians
Online Access:https://hdl.handle.net/10356/160735

Internet

https://hdl.handle.net/10356/160735

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