Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics

Biomacromolecules are highly promising therapeutic modalities to treat various diseases. However, they suffer from poor cellular membrane permeability, limiting their access to intracellular targets. Strategies to overcome this challenge often employ nanoscale carriers that can get trapped in endoso...

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Bibliographic Details
Main Authors: Sun, Yue, Lau, Sze Yi, Lim, Zhi Wei, Chang, Shi Chieh, Ghadessy, Farid, Partridge, Anthony, Miserez, Ali
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/161877