The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis

The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis

Lipid droplets (LDs) are implicated in conditions of lipid and protein dysregulation. The fat storage-inducing transmembrane (FIT; also known as FITM) family induces LD formation. Here, we establish a model system to study the role of the Saccharomyces cerevisiae FIT homologues (ScFIT), SCS3 and YFT...

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Bibliographic Details
Main Authors: Yap, Wei Sheng, Shyu Jr., Peter, Gaspar, Maria Laura, Jesch, Stephen A., Marvalim, Charlie, Prinz, William A., Henry, Susan A., Thibault, Guillaume
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Endoplasmic Reticulum-Associated Degradation
Lipid Droplet
Proteostasis
Phospholipid Metabolism
Unfolded Protein Response
Online Access:https://hdl.handle.net/10356/161980

Internet

https://hdl.handle.net/10356/161980

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