In vivo liquid-liquid phase separation protects amyloidogenic and aggregation-prone peptides during overexpression in Escherichia coli

In vivo liquid-liquid phase separation protects amyloidogenic and aggregation-prone peptides during overexpression in Escherichia coli

Studying pathogenic effects of amyloids requires homogeneous amyloidogenic peptide samples. Recombinant production of these peptides is challenging due to their susceptibility to aggregation and chemical modifications. Thus, chemical synthesis is primarily used to produce amyloidogenic peptides suit...

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Bibliographic Details
Main Authors: Gabryelczyk, Bartosz, Alag, Reema, Philips, Margaret, Low, Kimberly, Venkatraman, Anandalakshmi, Kannaian, Bhuvaneswari, Shi, Xiangyan, Linder, Markus, Pervushin, Konstantin, Miserez, Ali
Other Authors: School of Materials Science and Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Engineering::Materials
Science::Biological sciences
Amyloids
Membraneless Organelles
Online Access:https://hdl.handle.net/10356/162100

Internet

https://hdl.handle.net/10356/162100

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