Mechanistic insights into the membrane fouling mechanism during ultrafiltration of high-concentration proteins via in-situ electrical impedance spectroscopy (EIS)
Membrane fouling by the high protein concentrations used in the biopharmaceutical industry remains poorly understood. In this study, feed concentrations of up to 10,000 ppm of bovine serum albumin (BSA) were investigated with three polymeric membranes, two of which had the same molecular weight cut-...
Main Authors: | , , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/162121 |