Smart nano-PROTACs reprogram tumor microenvironment for activatable photo-metabolic cancer immunotherapy

Protease inhibitors can modulate intratumoral metabolic processes to reprogram the immunosuppressive tumor microenvironment (TME), which however suffer from the limited efficacy and off-targeted side effects. We report smart nano-proteolysis targeting chimeras (nano-PROTACs) with phototherapeutic ab...

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Bibliographic Details
Main Authors: Zhang, Chi, He, Shasha, Zeng, Ziling, Cheng, Penghui, Pu, Kanyi
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/162219