Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier

Currently, there is no effective method to prevent the formation of hypertrophic scars and keloids, which can cause severe physical and psychological burdens to patients. Secreted protein acidic and cysteine-rich (SPARC) is involved in wound fibrosis by modulating fibroblast functions, causing exces...

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Main Authors: Chun, Yong Yao, Tan, William Wei Ren, Vos, Marcus Ivan Gerard, Chan, Wen Kiat, Tey, Hong Liang, Tan, Nguan Soon, Tan, Timothy Thatt Yang
其他作者: School of Chemical and Biomedical Engineering
格式: Journal Article
语言:English
出版: 2022
主题:
在线阅读:https://hdl.handle.net/10356/162361