SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1

A recent mutation analysis suggested that Non-Structural Protein 6 (NSP6) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a key determinant of the viral pathogenicity. Here, by transcriptome analysis, we demonstrated that the inflammasome-related NOD-like receptor signaling wa...

ver descrição completa

Detalhes bibliográficos
Principais autores: Sun, Xiao, Liu, Yingzhi, Huang, Ziheng, Xu, Wenye, Hu, Wei, Yi, Lina, Liu, Zhe, Chan, Hung, Zeng, Judeng, Liu, Xiaodong, Chen, Huarong, Yu, Jun, Chan, Francis Ka Leung, Ng, Siew Chien, Wong, Sunny Hei, Wang, Maggie Haitian, Gin, Tony, Joynt, Gavin Matthew, Hui, David Shu Cheong, Zou, Xuan, Shu, Yuelong, Cheng, Christopher Hon Ki, Fang, Shisong, Luo, Huanle, Lu, Jing, Chan, Matthew Tak Vai, Zhang, Lin, Wu, William Ka Kei
Outros Autores: Lee Kong Chian School of Medicine (LKCMedicine)
Formato: Journal Article
Idioma:English
Publicado em: 2022
Assuntos:
Science::Medicine
ATP6AP1 Protein
Cryopyrin
Acesso em linha:https://hdl.handle.net/10356/162774

Internet

https://hdl.handle.net/10356/162774

Registros relacionados