Potential mechanism of xenobiotic seeding of TGFBIp fibrils and modified brain chaperones as therapy for TGFBI-associated corneal dystrophies
Transforming growth factor beta induced protein (TGFBIp) in the cornea undergoes proteolytic processing to produce peptides of uncertain physiological function with hereditary isoforms of the peptides giving rise to amyloidogenic corneal dystrophies (CD). This study explored the coacervation propens...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2022
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| Online Access: | https://hdl.handle.net/10356/162946 |