Expression of the full length NS2B integral membrane protein, a cofactor for dengue protease.
Polyprotein processing of dengue virus is performed by the host signal peptidase and virus encoded two-component protease consisting of NS3 and its cofactor NS2B. The exact mechanism by which NS2B cofactor stimulates the NS3 protease is not known and structure of complete NS2B is still lacking. To s...
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Format: | Final Year Project (FYP) |
Language: | English |
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2009
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Online Access: | http://hdl.handle.net/10356/16305 |