Ionic regulation of mycobacterial infection by potassium and potassium channel

Epigenetic analysis of monocytes from active TB patients demonstrated enrichment of KCNJ15, which encodes an inwardly rectifying K+ channel (Kir4.2). We investigated the function of Kir4.2 in mycobacterial infection using a gain and loss-of-function approach and knockout mouse model. Kir4.2 was obse...

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Bibliographic Details
Main Author: Lim, Carey Fang Hui
Other Authors: -
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163110