Src activates retrograde membrane traffic through phosphorylation of GBF1

Src activates retrograde membrane traffic through phosphorylation of GBF1

The Src tyrosine kinase controls cancer-critical protein glycosylation through Golgi to ER relocation of GALNTs enzymes. How Src induces this trafficking event is unknown. Golgi to ER transport depends on the GTP exchange factor (GEF) GBF1 and small GTPase Arf1. Here, we show that Src induces the fo...

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Bibliographic Details
Main Authors: Chia, Joanne, Wang, Shyi-Chyi, Wee, Sheena, Gill, David James, Tay, Felicia, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Gunaratne, Jayantha, Bard, Frederic A.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Biological sciences
Membrane Traffic
Signalling
Online Access:https://hdl.handle.net/10356/163234

Internet

https://hdl.handle.net/10356/163234

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