Src activates retrograde membrane traffic through phosphorylation of GBF1

The Src tyrosine kinase controls cancer-critical protein glycosylation through Golgi to ER relocation of GALNTs enzymes. How Src induces this trafficking event is unknown. Golgi to ER transport depends on the GTP exchange factor (GEF) GBF1 and small GTPase Arf1. Here, we show that Src induces the fo...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chia, Joanne, Wang, Shyi-Chyi, Wee, Sheena, Gill, David James, Tay, Felicia, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Gunaratne, Jayantha, Bard, Frederic A.
Άλλοι συγγραφείς: School of Biological Sciences
Μορφή: Journal Article
Γλώσσα:English
Έκδοση: 2022
Θέματα:
Διαθέσιμο Online:https://hdl.handle.net/10356/163234