Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury

The cytosolic protein rubicon (RUBCN) has been implicated in the removal of necrotic debris and autoimmunity. However, the role of RUBCN in models of acute kidney injury (AKI), a condition that typically involves necrotic kidney tubules, was not investigated. Here, we demonstrate that RUBCN-deficien...

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Detalhes bibliográficos
Principais autores: Tonnus, Wulf, Locke, Sophie, Meyer, Claudia, Maremonti, Francesca, Eggert, Lena, von Mässenhausen, Anne, Bornstein, Stefan R., Green, Douglas R., Linkermann, Andreas
Outros Autores: Lee Kong Chian School of Medicine (LKCMedicine)
Formato: Journal Article
Idioma:English
Publicado em: 2022
Assuntos:
Acesso em linha:https://hdl.handle.net/10356/163248