In-situ scalable manufacturing of Epstein-Barr virus-specific T-cells using bioreactor with an expandable culture area (BECA)
The ex-vivo expansion of antigen-specific T-cells for adoptive T-cell immunotherapy requires active interaction between T-cells and antigen-presenting cells therefore culture density and environment become important variables to control. Maintenance of culture density in a static environment is trad...
Main Authors: | Chen, Sixun, Ahmad Amirul Bin Abdul Rahim, Wang, Who-Whong, Cheong, Rachael, Prabhu, Akshaya V., Tan, Jerome Zu Yao, Naing, May Win, Toh, Han Chong, Liu, Dan |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Journal Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/163363 |
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