Enaminone formation drives the coupling of biosynthetic pathways to generate cyclic lipopeptides

A family of novel cyclic lipopeptides named tasikamides A􀀀 H (Tsk A􀀀 H) were discovered recently in Streptomyces tasikensis P46. Aside from the unique cyclic pentapeptide scaffold shared by the tasikamides, Tsk A􀀀 C contain a hydrazone bridge that connects the cyclic pentapeptide to the lipophil...

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Bibliographic Details
Main Authors: Candra, Hartono, Ma, Guang-Lei, Lee, Sean Qiu En, Liang, Zhao-Xun
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/163433