Identification and characterization of microRNA candidates that are upregulated by 5-aza-2’-deoxycytidine treatment in hepatocellular carcinoma cells.
MicroRNAs are small non-coding RNA of 19-20 nucleotides, capable of negatively regulating gene expression by targeting specific mRNA gene sequences, which causes mRNA degradation or inhibits protein translation. This study aims to investigate whether DNA hypermethylation may contribute to microRNA s...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/10356/16345 |