Carbene-catalyzed activation of C-Si bonds for chemo- and enantioselective cross Brook–Benzoin reaction

Carbene-catalyzed activation of C-Si bonds for chemo- and enantioselective cross Brook–Benzoin reaction

The first carbene-catalyzed asymmetric chemoselective cross silyl benzoin (Brook-Benzoin) reaction has been developed. Key steps of this reaction involve activation of the carbon-silicon bond of an acylsilane by a chiral N-heterocyclic carbene (NHC) catalyst to form a silyl acyl anion intermediate....

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Bibliographic Details
Main Authors: Tang, Chenghao, Wang, Wei, Luo, Guoyong, Song, Chaoyang, Bao, Zhaowei, Li, Pei, Hao, Gefei, Chi, Robin Yonggui, Jin, Zhichao
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
Acylsilanes
Benzoin Condensation
Online Access:https://hdl.handle.net/10356/163498

Internet

https://hdl.handle.net/10356/163498

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