Nuclear omics of mouse forebrain excitatory neurons in pilocarpine-induced seizures
An epileptic seizure generates massive neuronal activity in the brain which induces de novo transcription and translation, bringing about cellular changes which may contribute to epileptogenesis. To understand the cell-type-specific molecular changes brought about by seizures, I isolated nuclei from...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2022
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Online Access: | https://hdl.handle.net/10356/163613 |