Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents

Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents

Tuberculosis (TB) remains a leading cause of infectious disease-related mortality and morbidity. Pyrazinamide (PZA) is a critical component of the first-line TB treatment regimen because of its sterilizing activity against non-replicating Mycobacterium tuberculosis (Mtb), but its mechanism of action...

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Hlavní autoři: Hegde, Pooja V., Aragaw, Wassihun W., Cole, Malcolm S., Jachak, Gorakhnath, Ragunathan, Priya, Sharma, Sachin, Harikishore, Amaravadhi, Grüber, Gerhard, Dick, Thomas, Aldrich, Courtney C.
Další autoři: School of Biological Sciences
Médium: Journal Article
Jazyk:English
Vydáno: 2023
Témata:
Science::Biological sciences
Tuberculosis
Pyrazinoic Acid
On-line přístup:https://hdl.handle.net/10356/164677

Internet

https://hdl.handle.net/10356/164677

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