Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism

Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism

Cold affects many aspects of biology, medicine, agriculture, and industry. Here, we identify a conserved endoplasmic reticulum (ER) stress response, distinct from the canonical unfolded protein response, that maintains lipid homeostasis during extreme cold. We establish that the ER stress sensor IRE...

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Bibliographic Details
Main Authors: Dudkevich, Reut, Koh, Jhee Hong, Beaudoin-Chabot, Caroline, Celik, Cenk, Lebenthal-Loinger, Ilana, Karako-Lampert, Sarit, Syed Ahmad-Albukhari, Thibault, Guillaume, Henis-Korenblit, Sivan
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Caenorhabditis Elegans
ER Stress
RNA-Seq
Online Access:https://hdl.handle.net/10356/164688

Internet

https://hdl.handle.net/10356/164688

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