In vivo positron emission tomography imaging of mitochondrial abnormalities in a mouse model of tauopathy

In vivo positron emission tomography imaging of mitochondrial abnormalities in a mouse model of tauopathy

Damaged mitochondria may be one of the earliest manifestations of Alzheimer`s disease (AD). Since oxidative phosphorylation is a primary source of neuronal energy, unlike glycolysis-dependent energy production in inflamed glia, mitochondrial respiration could provide a selective biomarker of neurona...

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Bibliographic Details
Main Authors: Barron, Anna M., Ji, Bin, Fujinaga, Masayuki, Zhang, Ming-Rong, Suhara, Tetsuya, Sahara, Naruhiko, Aoki, Ichio, Tsukada, Hideo, Higuchi, Makoto
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences::Biochemistry
Functional Neuroimaging
Alzheimer's Disease
Online Access:https://hdl.handle.net/10356/164795

Internet

https://hdl.handle.net/10356/164795

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