Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1

Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1

Many viruses encode RNA-modifying enzymes to edit the 5' end of viral RNA to mimic the cellular mRNA for effective protein translation, genome replication, and evasion of the host defense mechanisms. Alphavirus nsP1 synthesizes the 5' end Cap-0 structure of viral RNAs. However, the molecul...

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Bibliographic Details
Main Authors: Zhang, Kuo, Law, Michelle Cheok Yien, Nguyen, Trinh Mai, Tan, Yaw Bia, Wirawan, Melissa, Law, Yee-Song, Jeong, Lak Shin, Luo, Dahai
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Medicine
Science::Biological sciences
mRNA
Chikungunya Virus
Online Access:https://hdl.handle.net/10356/164882

Internet

https://hdl.handle.net/10356/164882

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