Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency

Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency

Endogenous retroviruses (ERVs) have been reported to participate in pre-implantation development of mammalian embryos. In early human embryogenesis, different ERV sub-families are activated in a highly stage-specific manner. How the specificity of ERV activation is achieved remains largely unknown....

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Bibliographic Details
Main Authors: Ai, Zhipeng, Xiang, Xinyu, Xiang, Yangquan, Szczerbinska, Iwona, Qian, Yuli, Xu, Xiao, Ma, Chenyang, Su, Yaqi, Gao, Bing, Shen, Hao, Muhammad Nadzim Bin Ramli, Chen, Di, Liu, Yue, Hao, Jia-Jie, Ng, Huck Hui, Zhang, Dan, Chan, Yun-Shen, Liu, Wanlu, Liang, Hongqing
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Cell Potency
Naive and Primed Pluripotency
Online Access:https://hdl.handle.net/10356/164884

Internet

https://hdl.handle.net/10356/164884

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