Dendritic cell-intrinsic Ezh2 expression maintains thymic homeostasis and prevents premature thymic involution

Ezh2, a well-known histone methyltransferase, was previously shown to regulate the integrin-dependent migration of dendritic cells (DCs) via the non-canonical cytosolic methylation of the cytoskeleton protein Talin. It remained unclear if Ezh2 has other functional roles in DCs. Here, we found that D...

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Bibliographic Details
Main Author: Sint Thida Bo
Other Authors: Su I-Hsin
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/164947