Epigenetic and 3D chromatin landscape modulation from pluripotent to expanded-potential stem cells
The mechanisms underlying the gene regulation and enhancer-promoter rewiring which contribute to the transition of mouse embryonic stem cells (ESC) to totipotent-like expanded-potential stem cells (EPSCs) are still unknown. To obtain a comprehensive understanding of the totipotency, I show the exten...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/165360 |