Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy

Progesterone receptor (PGR) is a member of the nuclear receptor superfamily of transcription factors. It is critical for mammary stem cells expansion, mammary ductal branching and alveologenesis. The transcriptional activity of PGR is mainly mediated by activation functions AF1 and AF2. Although the...

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Bibliographic Details
Main Authors: Lee, Shi Hao, Yap, Yeannie H. Y., Lim, Chew Leng, Woo, Amanda Rui En, Lin, Valerie Chun Ling
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/165526