Modulating T-cell activation with antisense oligoucleotides targeting lymphocyte cytosolic protein 2

Modulating T-cell activation with antisense oligoucleotides targeting lymphocyte cytosolic protein 2

Dysregulated T-cell activation is a hallmark of several autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis (MS). The lymphocyte cytosolic protein 2 (LCP2), also known as SLP-76, is essential for the development and activation of T cells. Despite the critical role of LCP2 in...

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Bibliographic Details
Main Authors: Iyer, Vaishnavi Srinivasan, Boddul, Sanjaykumar V., Johnsson, Anna-Karin, Raposo, Bruno, Sharma, Ravi K., Shen, Yunbing, Kasza, Zsolt, Lim, Kah Wai, Chemin, Karine, Nilsson, Gunnar, Malmström, Vivianne, Phan, Anh Tuân, Wermeling, Fredrik
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2023
Subjects:
Science::Biological sciences
Antisense Oligonucleotides
T-Cell Activation
Online Access:https://hdl.handle.net/10356/165633

Internet

https://hdl.handle.net/10356/165633

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