Mechanisms of telomere regulation: characterizing TRF1-mediated phase separation of nucleosomes
Telomeres are functionally conserved regions at the ends of chromosomes that confer protection. The dysregulation of telomeres has been implicated in diseases of aging and cancer, but not all underlying mechanisms of telomere regulation have been fully elucidated. Recently, liquid-liquid phase separ...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/166549 |