Genetic modulators of Plasmodium falciparum parasites asexual fitness and resistance to clinical and preclinical compounds

Genetic modulators of Plasmodium falciparum parasites asexual fitness and resistance to clinical and preclinical compounds

Emergence of malarial Plasmodium falciparum KEL1/PLA1 co-lineage in Southeast Asia caused the failure of dihydroartemisin+piperaquine (DHA+PPQ). PfKelch (k13) C580Y mutation and plasmepsins 2/3 gene (pm2/3) amplification, markers of DHA and PPQ resistance respectively, are hallmarks of KEL1/PLA1 par...

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Bibliographic Details
Main Author: Hong, Davin
Other Authors: -
Format: Final Year Project (FYP)
Language:English
Published: Nanyang Technological University 2023
Subjects:
Science::Biological sciences::Microbiology::Drug Resistance
Science::Biological sciences::Genetics
Online Access:https://hdl.handle.net/10356/167504

Internet

https://hdl.handle.net/10356/167504

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