One-pot and unsymmetrical bis-allylation of malononitrile with conjugated dienes and allylic alcohols

One-pot and unsymmetrical bis-allylation of malononitrile with conjugated dienes and allylic alcohols

A Pd/Ca catalytic system to promote the unsymmetrical bis-allylation of malononitrile was developed by selecting conjugated dienes and allylic alcohols as allylic reagents. This catalytic system suppressed the competitive symmetrical bis-allylation process and guaranteed the desired unsymmetrical bi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Gao, Wenxiu, Zhang, Dong, Zhang, Xiaoyu, Cai, Xinying, Xie, Peizhong, Loh, Teck-Peng
Weitere Verfasser: School of Physical and Mathematical Sciences
Format: Journal Article
Sprache:English
Veröffentlicht: 2023
Schlagworte:
Science::Chemistry
Alcohols
Catalysts
Online Zugang:https://hdl.handle.net/10356/168950
Beschreibung
Zusammenfassung:A Pd/Ca catalytic system to promote the unsymmetrical bis-allylation of malononitrile was developed by selecting conjugated dienes and allylic alcohols as allylic reagents. This catalytic system suppressed the competitive symmetrical bis-allylation process and guaranteed the desired unsymmetrical bis-allylation with high chemoselectivity. A wide range of conjugated dienes and allylic alcohols were tolerated well in this transformation, and diverse 1,6-dienes were obtained with high efficiency.

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