One-pot and unsymmetrical bis-allylation of malononitrile with conjugated dienes and allylic alcohols

A Pd/Ca catalytic system to promote the unsymmetrical bis-allylation of malononitrile was developed by selecting conjugated dienes and allylic alcohols as allylic reagents. This catalytic system suppressed the competitive symmetrical bis-allylation process and guaranteed the desired unsymmetrical bi...

Повний опис

Бібліографічні деталі
Автори: Gao, Wenxiu, Zhang, Dong, Zhang, Xiaoyu, Cai, Xinying, Xie, Peizhong, Loh, Teck-Peng
Інші автори: School of Physical and Mathematical Sciences
Формат: Journal Article
Мова:English
Опубліковано: 2023
Предмети:
Онлайн доступ:https://hdl.handle.net/10356/168950
Опис
Резюме:A Pd/Ca catalytic system to promote the unsymmetrical bis-allylation of malononitrile was developed by selecting conjugated dienes and allylic alcohols as allylic reagents. This catalytic system suppressed the competitive symmetrical bis-allylation process and guaranteed the desired unsymmetrical bis-allylation with high chemoselectivity. A wide range of conjugated dienes and allylic alcohols were tolerated well in this transformation, and diverse 1,6-dienes were obtained with high efficiency.