Favorable preclinical pharmacological profile of a novel antimalarial pyrrolizidinylmethyl derivative of 4-amino-7-chloroquinoline with potent In vitro and In vivo activities
The 4-aminoquinoline drugs, such as chloroquine (CQ), amodiaquine or piperaquine, are still commonly used for malaria treatment, either alone (CQ) or in combination with artemisinin derivatives. We previously described the excellent in vitro activity of a novel pyrrolizidinylmethyl derivative of 4-a...
| Auteurs principaux: | , , , , , , , , , , , , , , |
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| Autres auteurs: | |
| Format: | Journal Article |
| Langue: | English |
| Publié: |
2023
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| Sujets: | |
| Accès en ligne: | https://hdl.handle.net/10356/169386 |